Fundamentals of linear systems analysis as applied to problems in biomedical modeling and instrumentation. Topics include properties of biomedical systems and signals; representation of continuous- and discrete-time signals and system response; convolution ; Fourier analysis in continuous and discrete domains; Laplace transform; frequency response and its application in biomedical systems; filter design; circuit analogs to mechanical and thermodynamics systems and their applications in modeling biomedical systems; applications in biomedical instrumentation; use of MATLAB to simulate and analyze biomedical linear systems. Prerequisites: GEEN 161, BMEN 310. (F;S)