Clinical Medicine I is part one of a three course series that presents organ system-based physiology, pathology, and pathophysiology. Each organ-specific block will review basic anatomy and related histology, normal function of that organ system, how the organ system is affected in response to disease, and how diseases of the organ system are treated. In Clinical Medicine I, the focus is on the clinical features, diagnosis, and corresponding treatment of most common disorders of dermatology, ophthalmology, otolaryngology, and musculoskeletal, rheumatology, cardiovascular and pulmonary medicine.