Antifungal activity of amidoxime surface functionalized electrospun polyacrylonitrile nanofibers

Nafisa Sirelkhatim; Dennis Lajeunesse; Ajit D. Kelkar; Lifeng Zhang

doi:10.1016/j.matlet.2014.11.090

Antifungal activity of amidoxime surface functionalized electrospun polyacrylonitrile nanofibers

Nafisa Sirelkhatim, Dennis Lajeunesse, Ajit D. Kelkar, Lifeng Zhang

Joint School of Nanoscience and Nanoengineering

Research output: Contribution to journal › Article › peer-review

Abstract

Amidoxime surface functionalized polyacrylonitrile (ASFPAN) nanofibers were prepared by electrospinning polyacrylonitrile (PAN) solution followed by surface treatment in hydroxylamine aqueous solution. The interaction between ASFPAN nanofibrous mat and fungus (yeast) was investigated for the first time and viability of yeast cells on the nanofibrous mat was evaluated. The biological assay revealed that yeast cells died on the ASFPAN nanofibrous mats after 30 min of contact while they were still alive on both of PAN and ASFPAN cast film. The observations indicated that differentiated cell adhesion on ASFPAN nanofibrous mat might be the reason for the death of yeast cells.

Original language	English
Pages (from-to)	217-220
Number of pages	4
Journal	Materials Letters
Volume	141
DOIs	https://doi.org/10.1016/j.matlet.2014.11.090
State	Published - Feb 15 2015

Keywords

Amidoxime
Cell growth
Electrospinning
Fiber technology
Yeast

Access to Document

10.1016/j.matlet.2014.11.090

Cite this

@article{91f7d96f175040948ca585576b7f7741,

title = "Antifungal activity of amidoxime surface functionalized electrospun polyacrylonitrile nanofibers",

abstract = "Amidoxime surface functionalized polyacrylonitrile (ASFPAN) nanofibers were prepared by electrospinning polyacrylonitrile (PAN) solution followed by surface treatment in hydroxylamine aqueous solution. The interaction between ASFPAN nanofibrous mat and fungus (yeast) was investigated for the first time and viability of yeast cells on the nanofibrous mat was evaluated. The biological assay revealed that yeast cells died on the ASFPAN nanofibrous mats after 30 min of contact while they were still alive on both of PAN and ASFPAN cast film. The observations indicated that differentiated cell adhesion on ASFPAN nanofibrous mat might be the reason for the death of yeast cells.",

keywords = "Amidoxime, Cell growth, Electrospinning, Fiber technology, Yeast",

author = "Nafisa Sirelkhatim and Dennis Lajeunesse and Kelkar, \{Ajit D.\} and Lifeng Zhang",

year = "2015",

month = feb,

day = "15",

doi = "10.1016/j.matlet.2014.11.090",

language = "English",

volume = "141",

pages = "217--220",

journal = "Materials Letters",

issn = "0167-577X",

}

TY - JOUR

T1 - Antifungal activity of amidoxime surface functionalized electrospun polyacrylonitrile nanofibers

AU - Sirelkhatim, Nafisa

AU - Lajeunesse, Dennis

AU - Kelkar, Ajit D.

AU - Zhang, Lifeng

PY - 2015/2/15

Y1 - 2015/2/15

N2 - Amidoxime surface functionalized polyacrylonitrile (ASFPAN) nanofibers were prepared by electrospinning polyacrylonitrile (PAN) solution followed by surface treatment in hydroxylamine aqueous solution. The interaction between ASFPAN nanofibrous mat and fungus (yeast) was investigated for the first time and viability of yeast cells on the nanofibrous mat was evaluated. The biological assay revealed that yeast cells died on the ASFPAN nanofibrous mats after 30 min of contact while they were still alive on both of PAN and ASFPAN cast film. The observations indicated that differentiated cell adhesion on ASFPAN nanofibrous mat might be the reason for the death of yeast cells.

AB - Amidoxime surface functionalized polyacrylonitrile (ASFPAN) nanofibers were prepared by electrospinning polyacrylonitrile (PAN) solution followed by surface treatment in hydroxylamine aqueous solution. The interaction between ASFPAN nanofibrous mat and fungus (yeast) was investigated for the first time and viability of yeast cells on the nanofibrous mat was evaluated. The biological assay revealed that yeast cells died on the ASFPAN nanofibrous mats after 30 min of contact while they were still alive on both of PAN and ASFPAN cast film. The observations indicated that differentiated cell adhesion on ASFPAN nanofibrous mat might be the reason for the death of yeast cells.

KW - Amidoxime

KW - Cell growth

KW - Electrospinning

KW - Fiber technology

KW - Yeast

UR - https://www.scopus.com/pages/publications/84918564563

U2 - 10.1016/j.matlet.2014.11.090

DO - 10.1016/j.matlet.2014.11.090

M3 - Article

SN - 0167-577X

VL - 141

SP - 217

EP - 220

JO - Materials Letters

JF - Materials Letters

ER -

Antifungal activity of amidoxime surface functionalized electrospun polyacrylonitrile nanofibers

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this