Chemical components of the roots of Noni (Morinda citrifolia) and their cytotoxic effects

Lishuang Lv; Huadong Chen; Chi-Tang Ho; Shengmin Sang

doi:10.1016/j.fitote.2011.02.008

Chemical components of the roots of Noni (Morinda citrifolia) and their cytotoxic effects

Lishuang Lv
, Huadong Chen
, Chi-Tang Ho
, Shengmin Sang

North Carolina Agricultural and Technical State University
Nanjing Normal University
Rutgers, Stt. Univ. of New Jersey

Research output: Contribution to journal › Article › peer-review

49 Scopus citations

Abstract

Roots of Morinda citrifolia (Noni or Yor in Thai) have been used traditionally for thousands of years to treat chronic diseases such as cancer and heart disease. In this study, three new anthraquinones together with 15 known compounds were isolated from the roots of M. citrifolia (Rubiaceae). Their structures were established by spectroscopic methods, particularly 1D and 2D NMR techniques. Six known compounds, together with two new compounds (2 and 3) showed significant inhibitory effects on the proliferation of human lung and colon cancer cells. © 2011 Elsevier B.V. All rights reserved.

Original language	English
Pages (from-to)	704-708
Number of pages	5
Journal	Fitoterapia
Volume	82
Issue number	4
DOIs	https://doi.org/10.1016/j.fitote.2011.02.008
State	Published - Jun 1 2011

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Anthraquinones
Morinda citrifolia
Noni
Proliferation of cancer cells

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10.1016/j.fitote.2011.02.008

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title = "Chemical components of the roots of Noni (Morinda citrifolia) and their cytotoxic effects",

abstract = "Roots of Morinda citrifolia (Noni or Yor in Thai) have been used traditionally for thousands of years to treat chronic diseases such as cancer and heart disease. In this study, three new anthraquinones together with 15 known compounds were isolated from the roots of M. citrifolia (Rubiaceae). Their structures were established by spectroscopic methods, particularly 1D and 2D NMR techniques. Six known compounds, together with two new compounds (2 and 3) showed significant inhibitory effects on the proliferation of human lung and colon cancer cells. {\textcopyright} 2011 Elsevier B.V. All rights reserved.",

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AU - Lv, Lishuang

AU - Chen, Huadong

AU - Ho, Chi-Tang

AU - Sang, Shengmin

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AB - Roots of Morinda citrifolia (Noni or Yor in Thai) have been used traditionally for thousands of years to treat chronic diseases such as cancer and heart disease. In this study, three new anthraquinones together with 15 known compounds were isolated from the roots of M. citrifolia (Rubiaceae). Their structures were established by spectroscopic methods, particularly 1D and 2D NMR techniques. Six known compounds, together with two new compounds (2 and 3) showed significant inhibitory effects on the proliferation of human lung and colon cancer cells. © 2011 Elsevier B.V. All rights reserved.

KW - Anthraquinones

KW - Morinda citrifolia

KW - Noni

KW - Proliferation of cancer cells

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Chemical components of the roots of Noni (Morinda citrifolia) and their cytotoxic effects

Abstract

UN SDGs

Keywords

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