TY - JOUR
T1 - Chemical components of the roots of Noni (Morinda citrifolia) and their cytotoxic effects
AU - Lv, Lishuang
AU - Chen, Huadong
AU - Ho, Chi-Tang
AU - Sang, Shengmin
PY - 2011/6/1
Y1 - 2011/6/1
N2 - Roots of Morinda citrifolia (Noni or Yor in Thai) have been used traditionally for thousands of years to treat chronic diseases such as cancer and heart disease. In this study, three new anthraquinones together with 15 known compounds were isolated from the roots of M. citrifolia (Rubiaceae). Their structures were established by spectroscopic methods, particularly 1D and 2D NMR techniques. Six known compounds, together with two new compounds (2 and 3) showed significant inhibitory effects on the proliferation of human lung and colon cancer cells. © 2011 Elsevier B.V. All rights reserved.
AB - Roots of Morinda citrifolia (Noni or Yor in Thai) have been used traditionally for thousands of years to treat chronic diseases such as cancer and heart disease. In this study, three new anthraquinones together with 15 known compounds were isolated from the roots of M. citrifolia (Rubiaceae). Their structures were established by spectroscopic methods, particularly 1D and 2D NMR techniques. Six known compounds, together with two new compounds (2 and 3) showed significant inhibitory effects on the proliferation of human lung and colon cancer cells. © 2011 Elsevier B.V. All rights reserved.
KW - Anthraquinones
KW - Morinda citrifolia
KW - Noni
KW - Proliferation of cancer cells
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79955465166&origin=inward
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U2 - 10.1016/j.fitote.2011.02.008
DO - 10.1016/j.fitote.2011.02.008
M3 - Article
C2 - 21356281
SN - 0367-326X
VL - 82
SP - 704
EP - 708
JO - Fitoterapia
JF - Fitoterapia
IS - 4
ER -
