Humoral response to calicivirus in captive tigers given a dual-strain vaccine

Tara M Harrison; Scott H Harrison; James G. Sikarskie; Douglas Armstrong

doi:10.1638/2012-0069R2.1

Humoral response to calicivirus in captive tigers given a dual-strain vaccine

Tara M Harrison
, Scott H Harrison
, James G. Sikarskie
, Douglas Armstrong

Michigan State University
Potter Park Zoo
Henry Doorly Zoo

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

The current feline vaccine with a single strain of calicivirus has been used for captive tigers, yet it may not protect against virulent systemic calicivirus infections. A cross-institutional study investigated the humoral response to a new dual-strain, killed-virus calicivirus vaccine for nine captive tigers. The subspecies of these tigers were Amur (Panthera tigris altaica), Bengal (Panthera tigris tigris), and Malayan (Panthera tigris jacksoni). Serum neutralization titers for virulent feline calicivirus strain FCV-DD1 were higher following dual-strain vaccine administration. There were no reports of adverse vaccine reactions. Dual-strain vaccination may afford broadened cross-protection against different calicivirus strains and is desirable to reduce the risk of virulent systemic calicivirus disease in tigers. © American Association of Zoo Veterinarians.

Original language	English
Pages (from-to)	23-28
Number of pages	6
Journal	Journal of Zoo and Wildlife Medicine
Volume	45
Issue number	1
DOIs	https://doi.org/10.1638/2012-0069R2.1
State	Published - Jan 1 2014

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Feline calicivirus
tiger
vaccine

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10.1638/2012-0069R2.1

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title = "Humoral response to calicivirus in captive tigers given a dual-strain vaccine",

abstract = "The current feline vaccine with a single strain of calicivirus has been used for captive tigers, yet it may not protect against virulent systemic calicivirus infections. A cross-institutional study investigated the humoral response to a new dual-strain, killed-virus calicivirus vaccine for nine captive tigers. The subspecies of these tigers were Amur (Panthera tigris altaica), Bengal (Panthera tigris tigris), and Malayan (Panthera tigris jacksoni). Serum neutralization titers for virulent feline calicivirus strain FCV-DD1 were higher following dual-strain vaccine administration. There were no reports of adverse vaccine reactions. Dual-strain vaccination may afford broadened cross-protection against different calicivirus strains and is desirable to reduce the risk of virulent systemic calicivirus disease in tigers. {\textcopyright} American Association of Zoo Veterinarians.",

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AU - Sikarskie, James G.

AU - Armstrong, Douglas

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AB - The current feline vaccine with a single strain of calicivirus has been used for captive tigers, yet it may not protect against virulent systemic calicivirus infections. A cross-institutional study investigated the humoral response to a new dual-strain, killed-virus calicivirus vaccine for nine captive tigers. The subspecies of these tigers were Amur (Panthera tigris altaica), Bengal (Panthera tigris tigris), and Malayan (Panthera tigris jacksoni). Serum neutralization titers for virulent feline calicivirus strain FCV-DD1 were higher following dual-strain vaccine administration. There were no reports of adverse vaccine reactions. Dual-strain vaccination may afford broadened cross-protection against different calicivirus strains and is desirable to reduce the risk of virulent systemic calicivirus disease in tigers. © American Association of Zoo Veterinarians.

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Humoral response to calicivirus in captive tigers given a dual-strain vaccine

Abstract

UN SDGs

Keywords

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