Abstract
Bay leaf belongs to the family Lauraceae, and it is one of the most popular culinary spices in all Western countries. Bay leaf has been used as herbal medicine and has pharmacological activity which includes anti-bacterial, anti-fungal, anti-diabetes and anti-inflammatory effects. The goal of this study was to identify compounds from Bay leaf (Laurus nobilis), which are responsible for inducing apoptosis using bioassay-directed isolation. The isolation of active compounds was carried out in three steps: multiple extractions, fractionation using column chromatography and purification using semi-preparative HPLC. The structure of separated compounds was determined on the basis of 1H, 13C nuclear magnetic resonance data, atmospheric pressure chemical ionization mass spectrometry data, and electron ionization mass spectrometry. Six compounds were identified; all of them are sesquiterpene lactones. © 2004 Elsevier Ltd. All rights reserved.
| Original language | English |
|---|---|
| Pages (from-to) | 497-501 |
| Number of pages | 5 |
| Journal | Food Chemistry |
| Volume | 93 |
| Issue number | 3 |
| DOIs | |
| State | Published - Dec 1 2005 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Bay leaf
- HPLC
- Laurus nobilis
- Mass spectrometry
- Sesquiterpene lactones
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