TY - JOUR
T1 - New unusual iridoids from the leaves of noni (Morinda citrifolia L.) show inhibitory effect on ultraviolet B-induced transcriptional activator protein-1 (AP-1) activity
AU - Sang, Shengmin
AU - Liu, Guangming
AU - He, Kan
AU - Zhu, Nanqun
AU - Dong, Zigang
AU - Zheng, Qunyi
AU - Rosen, Robert T.
AU - Ho, Chi-Tang
PY - 2003/6/12
Y1 - 2003/6/12
N2 - A novel iridoid dimer in whose structure the two iridoid units are connected by a rare ether group, together with two new unusual iridoids showing significant inhibition of UVB-induced Activator Protein-1 (AP-1) activity in cell cultures, have been isolated from the leaves of noni (Morinda citrifolia L.). Their structures were determined on the basis of detailed high-field 1D and 2D spectral analysis. Their inhibitory effect on UVB-induced transcriptional Activator Protein-1 (AP-1) activity are also discussed. © 2003 Elsevier Science Ltd. All rights reserved.
AB - A novel iridoid dimer in whose structure the two iridoid units are connected by a rare ether group, together with two new unusual iridoids showing significant inhibition of UVB-induced Activator Protein-1 (AP-1) activity in cell cultures, have been isolated from the leaves of noni (Morinda citrifolia L.). Their structures were determined on the basis of detailed high-field 1D and 2D spectral analysis. Their inhibitory effect on UVB-induced transcriptional Activator Protein-1 (AP-1) activity are also discussed. © 2003 Elsevier Science Ltd. All rights reserved.
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U2 - 10.1016/S0968-0896(03)00180-9
DO - 10.1016/S0968-0896(03)00180-9
M3 - Article
C2 - 12757717
SN - 0968-0896
VL - 11
SP - 2499
EP - 2502
JO - Bioorganic and Medicinal Chemistry
JF - Bioorganic and Medicinal Chemistry
IS - 12
ER -