Pleiotropic phenotypes of a Yersinia enterocolitica flhD mutant include reduced lethality in a chicken embryo model

Megan  K Townsend; Nathan  J Carr; Jyoti  G Iyer; Shelley  M Horne; Penelope  S Gibbs; Birgit  M Prüss

Pleiotropic phenotypes of a Yersinia enterocolitica flhD mutant include reduced lethality in a chicken embryo model

Megan K Townsend
, Nathan J Carr
, Jyoti G Iyer
, Shelley M Horne
, Penelope S Gibbs
, Birgit M Prüss

Biology

Research output: Contribution to journal › Article

Abstract

The Yersinia enterocolitica flagellar master regulator FlhD/FlhC affects the expression levels of non-flagellar genes, including 21 genes that are involved in central metabolism. The sigma factor of the flagellar system, FliA, has a negative effect on the expression levels of seven plasmid-encoded virulence genes in addition to its positive effect on the expression levels of eight of the flagellar operons. This study investigates the phenotypes of flhD and fliA mutants that result from the complex gene regulation.

Original language	English
Pages (from-to)	12
Journal	Unknown journal
Volume	8
State	Published - 2008

Cite this

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title = "Pleiotropic phenotypes of a Yersinia enterocolitica flhD mutant include reduced lethality in a chicken embryo model",

abstract = "The Yersinia enterocolitica flagellar master regulator FlhD/FlhC affects the expression levels of non-flagellar genes, including 21 genes that are involved in central metabolism. The sigma factor of the flagellar system, FliA, has a negative effect on the expression levels of seven plasmid-encoded virulence genes in addition to its positive effect on the expression levels of eight of the flagellar operons. This study investigates the phenotypes of flhD and fliA mutants that result from the complex gene regulation.",

author = "Townsend, \{Megan K\} and Carr, \{Nathan J\} and Iyer, \{Jyoti G\} and Horne, \{Shelley M\} and Gibbs, \{Penelope S\} and Pr{\"u}ss, \{Birgit M\}",

year = "2008",

language = "English",

volume = "8",

pages = "12",

journal = "Unknown journal",

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TY - JOUR

T1 - Pleiotropic phenotypes of a Yersinia enterocolitica flhD mutant include reduced lethality in a chicken embryo model

AU - Townsend, Megan K

AU - Carr, Nathan J

AU - Iyer, Jyoti G

AU - Horne, Shelley M

AU - Gibbs, Penelope S

AU - Prüss, Birgit M

PY - 2008

Y1 - 2008

N2 - The Yersinia enterocolitica flagellar master regulator FlhD/FlhC affects the expression levels of non-flagellar genes, including 21 genes that are involved in central metabolism. The sigma factor of the flagellar system, FliA, has a negative effect on the expression levels of seven plasmid-encoded virulence genes in addition to its positive effect on the expression levels of eight of the flagellar operons. This study investigates the phenotypes of flhD and fliA mutants that result from the complex gene regulation.

AB - The Yersinia enterocolitica flagellar master regulator FlhD/FlhC affects the expression levels of non-flagellar genes, including 21 genes that are involved in central metabolism. The sigma factor of the flagellar system, FliA, has a negative effect on the expression levels of seven plasmid-encoded virulence genes in addition to its positive effect on the expression levels of eight of the flagellar operons. This study investigates the phenotypes of flhD and fliA mutants that result from the complex gene regulation.

M3 - Article

VL - 8

SP - 12

JO - Unknown journal

JF - Unknown journal

ER -

Pleiotropic phenotypes of a Yersinia enterocolitica flhD mutant include reduced lethality in a chicken embryo model

Abstract

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