Polymeric coatings for biodegradable implants

Jessica Perkins, Zhigang Xu, Abhijit Roy, Prashant Kumta, Jenora Waterman, Salil Desai

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

In this research we investigate the effect of depositing different polymeric coatings on a biodegradable material. A precision droplet deposition process is utilized to coat poly(lactic-co-glycolic) acid (PLGA), polycaprolactone (PCL), and poly-ester urethane urea (PEUU) on magnesium alloy to control its corrosion characteristics. Inductively coupled plasma spectroscopy (ICP) was used to measure the release of magnesium ions from different coated samples. The magnesium alloy samples were exposed to normal human bronchial epithelial (NHBE) cells in media. PEUU and PLGA coatings showed higher corrosion resistance as compared to PCL coatings. PCL coatings offered minimal barrier protection and resulted in the formation of gas bubbles indicative of the corrosion reaction. This research lays a foundation for developing polymeric coatings to suit the corrosion characteristics of biodegradable materials for biomedical implants.

Original languageEnglish
Title of host publicationProceedings - MONTREAL'2014 AES-ATEMA
Subtitle of host publication17th AES-ATEMA International Conference on Advances and Trends in Engineering Materials and Their Applications, ATEMA MONTREAL 2014
EditorsYehia M. Haddad
PublisherAdvanced Engineering Solutions
Pages47-50
Number of pages4
ISBN (Electronic)9781927838020
StatePublished - 2014
Event17th AES-ATEMA International Conference on Advances and Trends in Engineering Materials and Their Applications, ATEMA MONTREAL 2014 - Montreal, Canada
Duration: Jun 16 2014Jun 20 2014

Publication series

NameAES-ATEMA International Conference Series - Advances and Trends in Engineering Materials and their Applications
Volume2014-January
ISSN (Print)1924-3642

Conference

Conference17th AES-ATEMA International Conference on Advances and Trends in Engineering Materials and Their Applications, ATEMA MONTREAL 2014
Country/TerritoryCanada
CityMontreal
Period06/16/1406/20/14

Keywords

  • Biodegradable implants
  • Corrosion control
  • Inkjet printing
  • Magnesium alloy
  • Polymeric coatings

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