Supramolecular end-group separation of linear polymers with different terminals through host-guest interaction

Jie Xue; Li Zhou; Peng He; Xinyuan Zhu; Deyue Yan; Xulin Jiang

doi:10.1007/s10847-007-9397-x

Supramolecular end-group separation of linear polymers with different terminals through host-guest interaction

Jie Xue
, Li Zhou
, Peng He
, Xinyuan Zhu
, Deyue Yan
, Xulin Jiang

Chemistry

Shanghai Jiao Tong University
Wuhan University

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

By increasing the hydrophobicity of end group, the complexation rate between α-cyclodextrin (α-CD) and poly(ethylene glycol) (PEG) derivative speeds up greatly. Based on such a huge difference of complexation kinetics, the PEG derivative with palmityloxy terminal (PEG-C16) can be successfully separated from a carboxylic acid end-functionalized analogue (PEG-COOH) by once supramolecular purification. Adding α-CD into the aqueous solution of PEG-C16/PEG-COOH mixture, PEG-C16 is encapsulated into α-CD cavity to form the crystalline inclusion complex in a very short time, while almost all of PEG-COOH molecules are still reserved in the aqueous solution. After dichloromethane extraction, the pure PEG-C16 is obtained. Moreover, the host CD can be recycled. Thus, it is an efficient green way to separate and purify the linear polymers with different terminal functionality. © 2007 Springer Science+Business Media B.V.

Original language	English
Pages (from-to)	83-88
Number of pages	6
Journal	Journal of Inclusion Phenomena and Macrocyclic Chemistry
Volume	61
Issue number	1-2
DOIs	https://doi.org/10.1007/s10847-007-9397-x
State	Published - Jun 1 2008

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title = "Supramolecular end-group separation of linear polymers with different terminals through host-guest interaction",

abstract = "By increasing the hydrophobicity of end group, the complexation rate between α-cyclodextrin (α-CD) and poly(ethylene glycol) (PEG) derivative speeds up greatly. Based on such a huge difference of complexation kinetics, the PEG derivative with palmityloxy terminal (PEG-C16) can be successfully separated from a carboxylic acid end-functionalized analogue (PEG-COOH) by once supramolecular purification. Adding α-CD into the aqueous solution of PEG-C16/PEG-COOH mixture, PEG-C16 is encapsulated into α-CD cavity to form the crystalline inclusion complex in a very short time, while almost all of PEG-COOH molecules are still reserved in the aqueous solution. After dichloromethane extraction, the pure PEG-C16 is obtained. Moreover, the host CD can be recycled. Thus, it is an efficient green way to separate and purify the linear polymers with different terminal functionality. {\textcopyright} 2007 Springer Science+Business Media B.V.",

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T1 - Supramolecular end-group separation of linear polymers with different terminals through host-guest interaction

AU - Xue, Jie

AU - Zhou, Li

AU - He, Peng

AU - Zhu, Xinyuan

AU - Yan, Deyue

AU - Jiang, Xulin

PY - 2008/6/1

Y1 - 2008/6/1

N2 - By increasing the hydrophobicity of end group, the complexation rate between α-cyclodextrin (α-CD) and poly(ethylene glycol) (PEG) derivative speeds up greatly. Based on such a huge difference of complexation kinetics, the PEG derivative with palmityloxy terminal (PEG-C16) can be successfully separated from a carboxylic acid end-functionalized analogue (PEG-COOH) by once supramolecular purification. Adding α-CD into the aqueous solution of PEG-C16/PEG-COOH mixture, PEG-C16 is encapsulated into α-CD cavity to form the crystalline inclusion complex in a very short time, while almost all of PEG-COOH molecules are still reserved in the aqueous solution. After dichloromethane extraction, the pure PEG-C16 is obtained. Moreover, the host CD can be recycled. Thus, it is an efficient green way to separate and purify the linear polymers with different terminal functionality. © 2007 Springer Science+Business Media B.V.

AB - By increasing the hydrophobicity of end group, the complexation rate between α-cyclodextrin (α-CD) and poly(ethylene glycol) (PEG) derivative speeds up greatly. Based on such a huge difference of complexation kinetics, the PEG derivative with palmityloxy terminal (PEG-C16) can be successfully separated from a carboxylic acid end-functionalized analogue (PEG-COOH) by once supramolecular purification. Adding α-CD into the aqueous solution of PEG-C16/PEG-COOH mixture, PEG-C16 is encapsulated into α-CD cavity to form the crystalline inclusion complex in a very short time, while almost all of PEG-COOH molecules are still reserved in the aqueous solution. After dichloromethane extraction, the pure PEG-C16 is obtained. Moreover, the host CD can be recycled. Thus, it is an efficient green way to separate and purify the linear polymers with different terminal functionality. © 2007 Springer Science+Business Media B.V.

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Supramolecular end-group separation of linear polymers with different terminals through host-guest interaction

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