Synthesis of nanoporous calcium carbonate spheres using double hydrophilic block copolymer poly(acrylic acid-b-N-isopropylacrylamide)

Sudhina Guragain; Nagy L. Torad; Yousef Gamaan Alghamdi; Abdulmohsen Ali Alshehri; Jeonghun Kim; Bishnu Prasad Bastakoti; Yusuke Yamauchi

doi:10.1016/j.matlet.2018.07.060

Synthesis of nanoporous calcium carbonate spheres using double hydrophilic block copolymer poly(acrylic acid-b-N-isopropylacrylamide)

Sudhina Guragain
, Nagy L. Torad
, Yousef Gamaan Alghamdi
, Abdulmohsen Ali Alshehri
, Jeonghun Kim
, Bishnu Prasad Bastakoti
, Yusuke Yamauchi

Chemistry

National Institute for Materials Science
Qingdao University of Science and Technology
King Abdulaziz University
The University of Queensland
Kyung Hee University

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

We report self-assembly of double hydrophilic block copolymer poly(acrylic acid-b-N-isopropylacrylamide) in aqueous solution. Self-assembly of calcium ions chelated complex micelles upon mineralization reaction forms calcium carbonate (CaCO3) sphere. High porosity on CaCO3 spheres can accommodate a large amount of anticancer drug (doxorubicin) and achieve sustainable drug release.

Original language	English
Pages (from-to)	143-147
Number of pages	5
Journal	Materials Letters
Volume	230
Issue number	Issue
DOIs	https://doi.org/10.1016/j.matlet.2018.07.060
State	Published - Nov 1 2018

Keywords

Calcium carbonate
Double hydrophilic block copolymer
Drug release
Micelles
Nanoporous materials

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10.1016/j.matlet.2018.07.060

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title = "Synthesis of nanoporous calcium carbonate spheres using double hydrophilic block copolymer poly(acrylic acid-b-N-isopropylacrylamide)",

abstract = "We report self-assembly of double hydrophilic block copolymer poly(acrylic acid-b-N-isopropylacrylamide) in aqueous solution. Self-assembly of calcium ions chelated complex micelles upon mineralization reaction forms calcium carbonate (CaCO3) sphere. High porosity on CaCO3 spheres can accommodate a large amount of anticancer drug (doxorubicin) and achieve sustainable drug release.",

keywords = "Calcium carbonate, Double hydrophilic block copolymer, Drug release, Micelles, Nanoporous materials",

author = "Sudhina Guragain and Torad, \{Nagy L.\} and Alghamdi, \{Yousef Gamaan\} and Alshehri, \{Abdulmohsen Ali\} and Jeonghun Kim and Bastakoti, \{Bishnu Prasad\} and Yusuke Yamauchi",

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T1 - Synthesis of nanoporous calcium carbonate spheres using double hydrophilic block copolymer poly(acrylic acid-b-N-isopropylacrylamide)

AU - Guragain, Sudhina

AU - Torad, Nagy L.

AU - Alghamdi, Yousef Gamaan

AU - Alshehri, Abdulmohsen Ali

AU - Kim, Jeonghun

AU - Bastakoti, Bishnu Prasad

AU - Yamauchi, Yusuke

PY - 2018/11/1

Y1 - 2018/11/1

N2 - We report self-assembly of double hydrophilic block copolymer poly(acrylic acid-b-N-isopropylacrylamide) in aqueous solution. Self-assembly of calcium ions chelated complex micelles upon mineralization reaction forms calcium carbonate (CaCO3) sphere. High porosity on CaCO3 spheres can accommodate a large amount of anticancer drug (doxorubicin) and achieve sustainable drug release.

AB - We report self-assembly of double hydrophilic block copolymer poly(acrylic acid-b-N-isopropylacrylamide) in aqueous solution. Self-assembly of calcium ions chelated complex micelles upon mineralization reaction forms calcium carbonate (CaCO3) sphere. High porosity on CaCO3 spheres can accommodate a large amount of anticancer drug (doxorubicin) and achieve sustainable drug release.

KW - Calcium carbonate

KW - Double hydrophilic block copolymer

KW - Drug release

KW - Micelles

KW - Nanoporous materials

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SN - 0167-577X

VL - 230

SP - 143

EP - 147

JO - Materials Letters

JF - Materials Letters

IS - Issue

ER -

Synthesis of nanoporous calcium carbonate spheres using double hydrophilic block copolymer poly(acrylic acid-b-N-isopropylacrylamide)

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Keywords

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