Synthesis of porous iron oxide microspheres by a double hydrophilic block copolymer

B. P. Bastakoti; Hiroaki Sukegawa; Kevin C.-W. Wu; Yusuke Yamauchi

doi:10.1039/c3ra47490a

Synthesis of porous iron oxide microspheres by a double hydrophilic block copolymer

B. P. Bastakoti
, Hiroaki Sukegawa
, Kevin C.-W. Wu
, Yusuke Yamauchi

Chemistry

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Porous microspheres of iron oxide (Fe2O3) are synthesized using a double hydrophilic block copolymer of poly(ethylene oxide)-block-poly(acrylic acid) (PEO-b-PAA). The PAA block with negative charge strongly interacts with ferric ions. The assembly of primary nanoparticles at elevated temperature forms the porous microsphere of Fe2O 3. The MTT assay of the microspheres based on HepG2 cell indicates good biocompatibility. The thorough porosity of microspheres can accommodate a large amount of anticancer drug cisplatin. © 2014 The Royal Society of Chemistry.

Original language	English
Pages (from-to)	9986-9989
Number of pages	4
Journal	RSC Advances
Volume	4
Issue number	20
DOIs	https://doi.org/10.1039/c3ra47490a
State	Published - Feb 26 2014

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abstract = "Porous microspheres of iron oxide (Fe2O3) are synthesized using a double hydrophilic block copolymer of poly(ethylene oxide)-block-poly(acrylic acid) (PEO-b-PAA). The PAA block with negative charge strongly interacts with ferric ions. The assembly of primary nanoparticles at elevated temperature forms the porous microsphere of Fe2O 3. The MTT assay of the microspheres based on HepG2 cell indicates good biocompatibility. The thorough porosity of microspheres can accommodate a large amount of anticancer drug cisplatin. {\textcopyright} 2014 The Royal Society of Chemistry.",

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AU - Sukegawa, Hiroaki

AU - Wu, Kevin C.-W.

AU - Yamauchi, Yusuke

PY - 2014/2/26

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AB - Porous microspheres of iron oxide (Fe2O3) are synthesized using a double hydrophilic block copolymer of poly(ethylene oxide)-block-poly(acrylic acid) (PEO-b-PAA). The PAA block with negative charge strongly interacts with ferric ions. The assembly of primary nanoparticles at elevated temperature forms the porous microsphere of Fe2O 3. The MTT assay of the microspheres based on HepG2 cell indicates good biocompatibility. The thorough porosity of microspheres can accommodate a large amount of anticancer drug cisplatin. © 2014 The Royal Society of Chemistry.

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Synthesis of porous iron oxide microspheres by a double hydrophilic block copolymer

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