TY - JOUR
T1 - The Association of Toxoplasma gondii with the Combination of Cardiovascular Disease, Chronic Kidney Disease, or Chronic Liver Disease: A Preliminary Study
AU - Babekir, Amani
AU - Mostafa, Sayed
AU - Obeng-Gyasi, Emmanuel
PY - 2023/12/1
Y1 - 2023/12/1
N2 - Toxoplasma gondii is a protozoan parasite widespread worldwide, with over 40 million individuals in the United States. It may infect vital organs such as the heart, kidneys, and liver, resulting in chronic infections. The main objective of this study is to investigate the association of Toxoplasma infection with the combination of cardiovascular disease, chronic kidney disease (CKD), or chronic liver disease (CLD). The National Health and Nutrition Examination Survey (NHANES 2009–2010) data were used, and the association of infection with chronic disease was assessed with biomarkers and indexes using statistical modeling. The percentage of participants with a combination of CLD and CKD was higher among Toxoplasma positive participants compared to the negative participants (2.76 vs. 1.26). Furthermore, exposure to T. gondii may increase the odds of cardiovascular disease, CKD, or CLD, or vice versa.
AB - Toxoplasma gondii is a protozoan parasite widespread worldwide, with over 40 million individuals in the United States. It may infect vital organs such as the heart, kidneys, and liver, resulting in chronic infections. The main objective of this study is to investigate the association of Toxoplasma infection with the combination of cardiovascular disease, chronic kidney disease (CKD), or chronic liver disease (CLD). The National Health and Nutrition Examination Survey (NHANES 2009–2010) data were used, and the association of infection with chronic disease was assessed with biomarkers and indexes using statistical modeling. The percentage of participants with a combination of CLD and CKD was higher among Toxoplasma positive participants compared to the negative participants (2.76 vs. 1.26). Furthermore, exposure to T. gondii may increase the odds of cardiovascular disease, CKD, or CLD, or vice versa.
KW - cardiovascular
KW - disease
KW - immune
KW - kidney
KW - liver
KW - Toxoplasma gondii
KW - U.S
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85175358036&origin=inward
UR - https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85175358036&origin=inward
U2 - 10.3390/medsci11040065
DO - 10.3390/medsci11040065
M3 - Article
C2 - 37873750
SN - 2076-3271
VL - 11
JO - Medical sciences (Basel, Switzerland)
JF - Medical sciences (Basel, Switzerland)
IS - 4
M1 - 65
ER -
